Genomic signatures of sex-biased demography: progress and prospects.

نویسندگان

  • Timothy H Webster
  • Melissa A Wilson Sayres
چکیده

Sex-biased demographic events have played a crucial role in shaping human history. Many of these processes affect genetic variation and can therefore leave detectable signatures in the genome because autosomal, X-linked, Y-linked, and mitochondrial DNA inheritance differ between sexes. Here, we discuss how sex-biased processes shape patterns of genetic diversity across the genome, review recent genomic evidence for sex-biased demography in modern human populations, and suggest directions for future research.

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عنوان ژورنال:
  • Current opinion in genetics & development

دوره 41  شماره 

صفحات  -

تاریخ انتشار 2016